Case study Archives - Polyplus Transfection

Gene expression

Plasmid DNA & mRNA transfection, Genome editing, Cell-specific DNA reagents

Genome editing

Delivery of gRNA and Cas9 for all systems

RNA interference

Transfection of siRNA, miRNA or other oligonucleotides

Protein production

Large scale TGE, high protein yields

Virus Production

Large scale virus production, clinical batches production, AAV, lentivirus

in vivo delivery

in vivo delivery of nucleic acids in various tissues of different animal models

Therapeutics

Reagents for preclinical and clinical trials in human, Therapeutics oligonucleotides

Molecular Biology & Diagnostics

PCR, primer, probe

Protein delivery

Intracellular delivery of proteins, peptides and blocking antibodies to live cells

Custom Services

Custom-made products, personnalized transfection services, custom quality controls

Products	Delivered Molecules				Cell types			Recommended use
Products	DNA	siRNA/miRNA	mRNA	Proteins	Adherent	Suspension	Specific	Recommended use
In vitro
jetOPTIMUS^{^®}							Hard to transfect cells	Research purpose
jetPRIME^{^®}								Research purpose
INTERFERin^{^®}								RNA interference
jetMESSENGER^{^®}							Hard to transfect cells	Research purpose
jetCRISPR™								CRISPR/Cas9 experiment
FectoPRO^{^®}							Suspension CHO & HEK-293	Protein production
FectoCHO™ Expression System							CHO cells	Protein production
PEIpro^{^®} Product Range							HEK-293	Virus Production
PEIpro^{^®}							HEK-293	Large-scale Virus Production
PEIpro^{^®}-HQ							HEK-293	Pre-clinical and early phase clinical virus production
PEIpro^{^®}-GMP							HEK-293	Clinical trials and commercialization
jetPEI^{^®}								High Throughput Screening Research purpose
jetPEI^{^®}-Macrophage							Primary macrophages, glial & dendritic cells	Cell specific
jetPEI^{^®}-Hepatocyte							Primary Hepatocytes	Cell specific
jetPEI^{^®}-HUVEC							Endothelial cells	Cell specific
PULSin								Proteofection
Products	Plasmid DNA	Oligo-nucleotides	mRNA	Proteins	Adherent	Suspension	Specific	Recommended use
In vivo
in vivo-jetPEI^{^®} Product Range								in vivo transfection
in vivo-jetPEI^{^®}								in vivo delivery to all organs
Preclinical and Cell Therapy reagents								Therapeutic in vivo delivery to all organs
*cGMP grade in vivo-jetPEI^{^®}*								Therapeutic in vivo delivery to all organs
in vivo-jetPEI^{^®}-Man								in vivo delivery delivery to mannose-receptor expressing tissue
in vivo-jetPEI^{^®}-Gal								in vivo delivery to liver
jetSI 10 mM								siRNA delivery to brain
Products	Plasmid DNA	Oligo-nucleotides	mRNA	Proteins	Adherent	Suspension	Specific	Recommended use
Other
SpCas9 Nuclease							CRISPR/Cas9 experiment
Zip Nucleic acid^{^®} (ZNA^{^®})							Molecular Biology & Diagnostics
STICKY SIRNA							Therapeutic siRNA
OLIGOPLUS and SIRNAPLUS^{^®}							Therapeutic cationic Oligonucleotides
Personalized transfection services							Transfection optimization
Custom-made products							in vitro transfection, therapeutics

For cell lines and references, please search the Polyplus-transfection Database.

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