INTERFERin® / jetPRIME® / in vivo-jetPEI®
Please feel free to browse the Polyplus-transfection Database to find conditions for specific product, cell line or nucleic acid type:
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Our in vivo-jetPEI® is a powerful polymer-based reagent, suited for delivery of oligonucleotides to any animal model. The protocol is similar to a classical transfection: the nucleic acid and the reagent are just mixed and administered to the animal.
Several types of molecules are abusively called miRNA. The term miRNA can refer to:
- mimic miRNA: these are structurally similar but not identical to siRNA and can be transfected with INTERFERin®.
- plasmid encoding for miRNA: this molecule can be transfected using jetPRIME®.
- antimiR: this is a single-stranded nucleic acid designed to specifically bind to and inhibit endogenous microRNA; it can be transfected using INTERFERin®.
For the same amount of transfected oligonucleotide, the number of delivered copies will be different depending on the oligonucleotide size (longer oligonucleotide: less copies, shorter oligonucleotide: more copies). Therefore, oligonucleotide amounts should be adjusted accordingly.