Meet our team at the booth #406 during Peptalk USA, in San Diego (USA), January 14th-18th, 2019.
Our solutions for both protein and virus production
FectoPRO® Transfection kit is specifically designed for enhanced Transient Gene Expression (TGE) in suspension CHO and HEK-293 cells in various serum-free media, using low DNA amount (< 1 µg/ml of cell culture).
FectoCHO™ Expression system is a 3 component kit optimized to work together that contains FectoCHO™ CD Medium, FectoPRO® Transfection Reagent and FectoPRO® Expression Booster. FectoCHO™ Expression System has been developed to reach the highest protein production ever seen in CHO cell lines.
PEIpro® is a DNA transfection reagent for production of viruses, recombinant proteins and antibodies either in adherent cells in presence of serum or in suspension HEK-293 cells grown in low serum or serum-free media.
PEIpro®-HQ is a highly qualified grade of PEIpro® DNA transfection reagent. Process development are guaranteed to be seamlessly applicable with PEIpro®-HQ for manufacturing of viral vectors for pre-clinical and early phase clinical trial.
PEIpro®-GMP (NEW) is the highest quality grade PEI and the only transfection reagent available on the market supplied in a bag, ideal for GMP-compliant closed system manufacturing of clinical grade therapeutic viral vector,
Advanced CHO Cell Expression System for Increased Transient Protein Production.
The growing need in the biopharmaceutical market for various recombinant proteins and antibodies produced in a short time requires an efficient and flexible system. Transient expression is a commonly used process to face this demand but is unfortunately limited by transfection efficiency and inherent productivity, especially with CHO cells. To overcome this issue, we developed an advanced transient expression system consisting in the synergistic association of a novel CHO chemically defined medium and a powerful transfection reagent. First, we show that this innovative medium allows easy cultivation of various strains of CHO cells without the need of an extensive sequential adaptation. In a second time, through the protocol optimization of a technologically advanced transfection solution, we demonstrate a major increase in our recombinant proteins yields.
Addressing Large-Scale Manufacturing of Clinical Grade Viral Vectors Using an Optimized PEI-based Transfection Process: PEIpro®
With the progress in developing new viral vector systems guided by safety, specificity and potency considerations, several gene and cell-based therapies are now more than ever closer to being clinically approved and commercially available to treat genetic diseases. Viral vector delivery systems, of which mainly adeno-associated viruses (AAV) and lentiviruses are produced by transient transfection of mammalian producer HEK-293 cell lines. Virus vector production using the right transient transfection method is crucial to provide the flexibility and reproducibility that is needed to scale-up from initial process development to manufacturing of high-quality grade viral vectors.
Meet Julien Depollier and Géraldine Guerin-Peyrou to discuss on how to improve your process of Bioproduction. We will be happy to answer all your questions regarding transfection and to present relevant products adapted to protein or virus production.
The convention took place at Hilton San Diego Bayfront:
1 Park Blvd, San Diego, CA, United States
For more information, please have a look at the agenda and register now to meet the delivery experts. Two Posters will be presented focusing on FectoPRO® (Protein production) and PEIpro® (Virus production).
Join us on the social network
We created a dedicated event on Facebook to allow you to discuss with other scientists about the PepTalk meeting or about your transfection experiments.
If you want to talk about this event (Facebook, Twitter, Google+, etc…), don’t forget to use the #PTK19 and follow the PepTalk news.