Summary
Our team
Bioproduction R&D Manager
Talk: Next-Generation Transfection Reagent for Large Scale AAV Manufacturing
Transient transfection of suspension cells is the most commonly used production platform for AAV manufacturing.
However, this method shows some limitations in large scale bioreactors: inadequate transfection protocol, reduced transfection efficiency and lower productivity. To address this concern, we present data on the novel transfection reagent showing: i) increased AAV titers, ii) improved transfection protocol for large scale bioreactors and iii) reproducibility of viral titers at different production scale.
Presented by Mathieu Porte, R&D Production Manager at Polyplus-transfection®
September 21 , 1:00 – 1:30 PM PST
Our solutions for both protein and virus production
NEW! FectoVIR®-AAV: for Recombinant AAV virus production in suspension cells.
PEIpro® product range for a scalable viral vector production for Gene & Cell therapy.
FectoPRO® Transfection kit is specifically designed for enhanced Transient Gene Expression (TGE) in suspension CHO and HEK-293 cells in various serum-free media, using low DNA amount (< 1 µg/ml of cell culture).