• Authors: Cloutier P. et al.
  • Year: 2020
  • Journal: J Proteome Res 19 18-27
  • Applications: in vitro / DNA / jetPRIME
  • Cell type: Flp-In T-REx 293


The PAQosome is an 11-subunit chaperone involved in the biogenesis of several human protein complexes. We show that ASDURF, a recently discovered upstream open reading frame (uORF) in the 5' UTR of ASNSD1 mRNA, encodes the 12th subunit of the PAQosome. ASDURF displays significant structural homology to