Citation

  • Authors: Coller JB. et al.
  • Year: 2019
  • Journal: Cell Mol Life Sci
  • Applications: in vivo / miRNA / in vivo-jetPEI

Method

Complexation by vortexing and 15-20 min RT.

Abstract

Prior studies have established the important role of extracellular signal-regulated kinase 1/2 (ERK1/2) as a mediator of acute kidney injury (AKI). We demonstrated rapid ERK1/2 activation induced renal dysfunction following ischemia/reperfusion (IR)-induced AKI and downregulated the mitochondrial biogenesis (MB) regulator, peroxisome proliferator-activated receptor

Pubmed