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Home > Therapeutics

Application : Therapeutics
Therapeutics

Polyplus-transfection®‘s reagents are used in a growing number of preclinical and clinical trials, making us a worldwide leader with extensive expertise in in vivo delivery of nucleic acids. To support the development of new therapies based on the delivery of nucleic acids, Polyplus-transfection® supplies reagents manufactured in compliance with applicable European Commission and FDA guidelines for preclinical studies as well as for clinical trials phase I to III.

In addition, Polyplus-transfection® offers novel classes of modified oligonucleotides available for licensing for a wide range of applications including therapeutic purposes.

Injectable in vivo transfection reagent
in vivo-jetPEI®-PC
Non-viral delivery reagent for Human Gene Therapy
GMP in vivo-jetPEI®
Pre-clinical and early phase clinical virus production
PEIpro®-HQ
The highest quality grade for therapeutic virus production
PEIpro®-GMP
Cationic Oligonucleotides
OLIGOPLUS and SIRNAPLUS®
Therapeutic siRNA
STICKY SIRNA
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67400 Illkirch
FRANCE

Ph: +33 (0)3 90 40 61 80

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NY 10020 USA

 

Applications
  • Gene expression
  • Genome editing
  • RNA interference
  • Protein production
  • Virus Production
  • in vivo delivery
  • Therapeutics
  • Molecular Biology & Diagnostics
  • Protein delivery
  • Custom Services
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AFAQ - ISO 9001 2019 - Copyright Polyplus Transfection®
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Gene expression
Gene expression
Plasmid DNA & mRNA transfection, Genome editing, Cell-specific DNA reagents
Genome editing
Genome editing
Delivery of gRNA and Cas9 for all systems
RNA interference
RNA interference
Transfection of siRNA, miRNA or other oligonucleotides
Protein production
Protein production
Large scale TGE, high protein yields
Virus Production
Virus Production
Large scale virus production, clinical batches production, AAV, lentivirus
in vivo delivery
in vivo delivery
in vivo delivery of nucleic acids in various tissues of different animal models
Therapeutics
Therapeutics
Reagents for preclinical and clinical trials in human, Therapeutics oligonucleotides
Molecular Biology & Diagnostics
Molecular Biology & Diagnostics
PCR, primer, probe
Protein delivery
Protein delivery
Intracellular delivery of proteins, peptides and blocking antibodies to live cells
Custom Services
Custom Services
Custom-made products, personnalized transfection services, custom quality controls
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Products Delivered Molecules Cell types Recommended use
DNA siRNA/miRNA mRNA Proteins  Adherent  Suspension Specific
In vitro
jetOPTIMUS® Hard to transfect cells Research purpose
jetPRIME® Research purpose
INTERFERin® RNA interference
jetMESSENGER® Hard-to-transfect cells Research purpose
jetCRISPR® CRISPR/Cas9 experiment
FectoPRO® Suspension CHO & HEK-293 Protein production
FectoCHO® Expression System CHO cells Protein production
PEIpro® Product Range HEK-293 Virus Production
PEIpro® HEK-293 Large-scale Virus Production
PEIpro®-HQ HEK-293 Pre-clinical and early phase clinical virus production
PEIpro®-GMP HEK-293 Clinical trials and commercialization virus production
jetPEI® High Throughput Screening Research purpose
jetPEI®-Macrophage Primary macrophages, glial & dendritic cells Cell specific
jetPEI®-Hepatocyte Primary Hepatocytes Cell specific
jetPEI®-HUVEC Endothelial cells Cell specific
PULSin Proteofection
Products Plasmid DNA Oligo-nucleotides mRNA Proteins Adherent Suspension Specific Recommended use
In vivo
in vivo-jetRNA® in vivo mRNA transfection
in vivo-jetPEI® Product Range in vivo transfection
in vivo-jetPEI® in vivo transfection to all organs
in vivo-jetPEI®-PC Injectable in vivo transfection reagent
GMP in vivo-jetPEI® Therapeutic in vivo transfection to all organs
in vivo-jetPEI®-Man in vivo delivery to mannose-receptor expressing tissue
in vivo-jetPEI®-Gal in vivo delivery to liver
jetSI 10 mM siRNA transfection to brain
Products Plasmid DNA Oligo-nucleotides mRNA Proteins Adherent Suspension Specific Recommended use
Other
SpCas9 Nuclease CRISPR/Cas9 experiment
Zip Nucleic acid® (ZNA®) Molecular Biology & Diagnostics
STICKY SIRNA Therapeutic siRNA
OLIGOPLUS and SIRNAPLUS® Therapeutic cationic Oligonucleotides
Personalized transfection services Transfection optimization
Custom-made products in vitro transfection, therapeutics
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For cell lines and references, please search the Polyplus-transfection Database.

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