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Application : Therapeutics
Therapeutics

Polyplus-transfection®‘s reagents are used in a growing number of preclinical and clinical trials, making us a worldwide leader with extensive expertise in in vivo delivery of nucleic acids. To support the developpment of new therapies based on the delivery of nucleic acids, Polyplus-transfection® supplies reagents manufactured in compliance with applicable European Commission and FDA guidelines for preclinical studies as well as for clinical trials phase I to III.

In addition, Polyplus-transfection® offers novel classes of modified oligonucleotides available for licensing for a wide range of applications including therapeutic purposes.

Nucleic acid delivery reagents
Preclinical and Cell Therapy reagents
Nucleic acid delivery reagent for clinical trials
cGMP grade in vivo-jetPEI®
Therapeutic siRNA
STICKY SIRNA
Cationic Oligonucleotides
OLIGOPLUS and SIRNAPLUS®
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850 bd Sébastien Brant
67400 Illkirch
FRANCE

1251 Ave of the Americas
3rd Fl, New York
NY 10020 USA

Ph: +33 (0)3 90 40 61 80
Fax: +33 (0)3 90 40 61 81

Applications
  • Gene expression
  • Genome editing
  • RNA interference
  • Protein production
  • Virus Production
  • in vivo delivery
  • Therapeutics
  • Molecular Biology & Diagnostics
  • Protein delivery
  • Custom Services
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AFAQ - ISO 9001 2018 - Copyright Polyplus Transfection®
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Gene expression
Gene expression
Plasmid DNA & mRNA transfection, Genome editing, Cell-specific DNA reagents
Genome editing
Genome editing
Delivery of gRNA and Cas9 for all systems
RNA interference
RNA interference
Transfection of siRNA, miRNA or other oligonucleotides
Protein production
Protein production
Large scale TGE, high protein yields
Virus Production
Virus Production
Large scale virus production, clinical batches production, AAV, lentivirus
in vivo delivery
in vivo delivery
in vivo delivery of nucleic acids in various tissues of different animal models
Therapeutics
Therapeutics
Reagents for preclinical and clinical trials in human, Therapeutics oligonucleotides
Molecular Biology & Diagnostics
Molecular Biology & Diagnostics
PCR, primer, probe
Protein delivery
Protein delivery
Intracellular delivery of proteins, peptides and blocking antibodies to live cells
Custom Services
Custom Services
Custom-made products, personnalized transfection services, custom quality controls
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Products Delivered Molecules Cell types Recommended use
DNA siRNA/miRNA mRNA Proteins Adherent Suspension Specific
In vitro
jetPRIME® Research purpose
INTERFERin® RNA interference
jetMESSENGER® Hard to transfect cells Research purpose
jetCRISPR™ CRISPR/Cas9 experiment
FectoPRO® Suspension CHO & HEK-293 Protein production
PEIpro® HEK-293 Virus production
PEIpro®-HQ HEK-293 Production of clinical batches viruses and proteins
jetPEI® High Throughput Screening Research purpose
jetPEI®-Macrophage Primary macrophages, glial & dendritic cells Cell specific
jetPEI®-Hepatocyte Primary Hepatocytes Cell specific
jetPEI®-HUVEC Endothelial cells Cell specific
PULSin Proteofection
Products Plasmid DNA Oligo-nucleotides mRNA Proteins Adherent Suspension Specific Recommended use
In vivo
in vivo-jetPEI® in vivo delivery to all organs
Preclinical and Cell Therapy reagents Therapeutic in vivo delivery to all organs
cGMP grade in vivo-jetPEI® Therapeutic in vivo delivery to all organs
in vivo-jetPEI®-Man in vivo delivery delivery to mannose-receptor expressing tissue
in vivo-jetPEI®-Gal in vivo delivery to liver
jetSI 10 mM siRNA delivery to brain
Products Plasmid DNA Oligo-nucleotides mRNA Proteins Adherent Suspension Specific Recommended use
Other
SpCas9 Nuclease CRISPR/Cas9 experiment
Zip Nucleic acid® (ZNA®) Molecular Biology & Diagnostics
STICKY SIRNA Therapeutic siRNA
OLIGOPLUS and SIRNAPLUS® Therapeutic cationic Oligonucleotides
Personalized transfection services Transfection optimization
Custom-made products in vitro transfection, therapeutics
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For cell lines and references, please search the Polyplus-transfection Database.

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