RNA interference

Delivering oligonucleotides like siRNA or miRNA allows for RNA interference or gene regulation in live cells, and therefore to investigate the role of endogenous genes in signaling and metabolic pathways either at lab scale or in high-throughput screening. Furthermore, co-transfection of plasmid DNA with oligonucleotides like siRNA or miRNA is conveniently used to study the modulation of exogenous genes. For each of these applications, Polyplus-transfection designed and developed specific solutions.